why weight loss diets don’t work for everyone?

Most patients who come for a consultation for weight loss to bariatric surgery clinics have usually tried multiple weight loss programs and diets before. The story is the same every time. They lose weight when they hit a wall and the weight loss plateaus. They persist with the diet for some more time. Eventually, they get demotivated and stop the diet. The weight comes rushing back, sometimes more than what they have lost. The entire exercise leads to very pronounced feelings of guilt, demotivation self-blame. Unfortunately, this cycle gets repeated multiple times in the weight loss journeys of people living with leading to extreme frustration and disappointment, unlike other chronic conditions, obesity is highly misunderstood. Most people think that obesity is a self-inflicted condition and somehow those who suffer from it have brought it upon themselves. It is commonly associated with gluttony and sloth. However, nothing could be further from the truth Laparoscopic Surgeon “Human body very we remain alive due to an interplay of multiple feedback mechanisms and control systems. When all of this is working as it should, we maintain good health. However, if any of these control systems and feedback mechanisms go awry, it results in a disease.” that makes weight gain possible even with a detour understanding of obesity is still not complete, however, some of the mechanisms that defeat a diet and lead to weight gain are listed below is the appetite-inducing hormone. Obesity is associated with decreased post-meal suppression of ghrelin hormone is not the cause of obesity, but an effect of raised ghrelin levels. Weight loss diets lead to an increase in the levels of leading to increased hunger and cravings like GLP 1 and affect appetite suppression, satiety, hunger, blood glucose regulation, and so on. Weight loss diets lead to a decrease in the levels of GLP1 and lead to lesser satiety, increased hunger, and cravings. Obesity is also associated with insulin and leptin resistance. These hormones in energy balance and weight regulation respond to food in people with obesity. The reward pathway or the hedonic pathway is a neurological pathway controlled by the hypothalamus in the human brain. Stimulation of the central hedonic pathway can alter the eating with obesity and may sometimes override the signals of hunger and satiety and tend to defeat weight loss diets gut microbiome has been proven in multiple studies that the bacterial lining of people with obesity is different from lean people. Obesity is associated with a relative increase or decrease in certain bacterial species. This important role play in plays a role in glucose and energy balance. In addition to all their other actions, they also help in the activation of GLP 1. In patients with obesity, circulating bile acid levels are impaired in an inflammatory state that can affect the taste buds on the tongue. People with obesity tend to have less sensitivity to sweet taste and may consume a lot sweeter to get the same taste perception. There is a close interaction between energy balance, taste, and smell signals have been established that almost 70% of obesity can be attributed to genetics. Obesity can be monogenic, and polygenic. Polygenic obesity is the most common. This theory states that the human body tries to maintain its weight within a preferred range and every time we tend to lose weight, the body tends to spring back to the set weight from all the factors listed above, the homeostatic mechanisms of the human body tend to defend the high weight and make it more difficult to lose weight. While diet and lifestyle modification remain the foundation of all weight loss modalities, it is incorrect to think that diet and exercise alone will be enough to treat every stage of obesity. Diets are an effective treatment option for people who are overweight or have grade 1 obesity. In people with severe obesity, these feedback and regulatory mechanisms are defective, and diet alone cannot help them. Diet is neither the only diet is also imperative to understand that obesity is not self-inflicted. It has nothing to do with willpower. It is as much of a disease as any other and needs to be treated methodically and in to get effective results.