Globally, cancer is a major health issue, responsible for one out of every six deaths. While new treatment techniques have shown promising results, it’s a long way before such treatments are made available to the masses. Some of the most common cancers are breast cancer, lung cancer, prostate cancer, colon cancer, melanoma of the skin, leukemia, pancreatic cancer, thyroid cancer and liver cancer. As is evident, cancer can affect almost all parts of the body.
However, if you read carefully, you will notice that heart is not there in the list of most common cancers. It makes us wonder why heart remains largely protected from cancer, even when it’s among the most important organs of the body. Here are some facts that explain why heart cancer is so rare.
How rare is heart cancer?
As per estimates, tumors that originate in the heart are as low as 1.38 for every 100,000 people every year. Statistically, number of heart cases are so low that it cannot be determined to occur at a measurable rate. Experts say that a heart surgeon might encounter a case of heart cancer only around once in their entire career.
Type of tissue
One of the key things that makes heart unique is the nature of its tissue. Heart largely comprises of connective tissue, which is not prone to cancerous growth. That’s because cell division is very little in connective tissue. Heart cells don’t replicate unless there is a need to repair, arising from any type of injury. Since there is so little cell division, the heart remains largely protected from cancer.
For cancer to spread, it will need epithelial tissue that is consistently producing new cells. Epithelial tissue can be found in most organs such as breast, colon, skin, prostate, pancreas, stomach, esophagus, etc. As epithelial cells are constantly making new cells, it provides a breeding ground for cancer cells to grow and replicate.
Limited exposure to carcinogens
As compared to other parts of the body, the heart has limited exposure to carcinogens. These are substances that have potential to cause cancer in living tissue. The only carcinogens heart may be exposed to are the ones present in the blood. In comparison, body parts such as skin, colon, stomach, liver and lungs face much greater exposure to carcinogens on an everyday basis.
While you are unlikely to be affected by heart cancer, there are several other things to worry about. For example, heart is prone to various health issues such as hypertension and atherosclerotic disease. Your heart can also experience issues with its pumping function and electrical system. Due to these factors, it is imperative that you take proper care of your heart. Eating a healthy diet, avoiding junk food, regular exercise and good sleep can help reduce risk of heart disease.
Cancer that begins in the heart is most often sarcoma, a type of cancer that originates in the soft tissues of the body. But some heart tumors can be cancerous. Heart cancer (malignant primary cardiac tumor) is extremely rare. Most tumors that form in the heart aren't cancerous.
This rare cancer causes heart failure, pericarditis and arrhythmias. Heart cancer results from a heart tumor like angiosarcoma or another cancer that spreads to the heart. Cancer can spread to the heart from organs or through the blood (leukemia). Chemotherapy, radiation therapy, and surgery shrink or remove heart tumors, ease symptoms, and may prolong life.
Question and Answer :
What is heart cancer?
Heart cancer occurs when diseased cells grow out of control on or near the heart. These cells form a tumor. Cancer that begins in the heart is primary heart cancer. This form of heart cancer is extremely rare.
Heart cancer more commonly occurs when cancer cells spread to the heart from cancer in a nearby organ. For example, lung cancer may spread to the heart, causing secondary heart cancer. Cancer that spreads is metastatic cancer.
How common is heart cancer?
Primary heart cancer affects fewer than 2 out of 100,000 people every year. Cardiac tumors are rare. An estimated 8 out of 10 tumors that affect the heart are benign (not cancer).
Why is heart cancer so rare?
The heart is made of connective tissue and muscle cells that do not turn over very fast, which makes them very resistant to becoming cancerous. Cancer cells grow and multiply more vigorously in epithelial tissue that tends to turn over more quickly and so is more susceptible to a mutation (error in replication) occurring that can lead to cancer.
Epithelial tissue lines most organs. The breasts also have this tissue. For this reason, cancer more commonly affects tissue in the breasts and organs like the colon, pancreas, lungs and skin.
Who might get heart cancer?
Anyone can get heart cancer. The disease is more likely to affect men aged 30 to 50, but only slightly more often than in women. People who smoke or have AIDS may be more at risk but the data is limited.
What causes heart cancer?
Angiosarcoma, a rare type of malignant (cancerous) soft tissue tumor, causes 9 out of 10 primary heart cancers in adults. The cause of angiosarcoma is unknown, although radiation and some toxins may play a role. Other subtypes of sarcoma cancerous tumors can also occur in the heart and great vessels (aorta, pulmonary arteries).
Is heart cancer inherited?
Angiosarcomas of the heart sometimes affect multiple members of the same family. Scientists believe that certain people are more prone to this primary heart cancer because of their genes, but we are still learning about the genetic basis of most of these cancers.
The cause may be related to a mutation (change) in a gene called protection of telomeres protein 1 (POT1). A parent with this gene mutation can pass it to their children.
What are the symptoms of heart cancer?
Sudden unexplained heart failure is a top sign of heart cancer. You may experience shortness of breath and extreme fatigue if the tumor is pressing on a chamber of the heart or growing within the heart and affecting valve function.
Other symptoms of heart cancer include:
- Arrhythmia (abnormal heart rhythm) or rapid heart rate.
- Chest pain.
- Fainting.
Many cardiac tumors are found incidentally on an imaging study like an echocardiogram (heart ultrasound) or CT scan or MRI done for another reason.
Primary heart cancer can spread to other parts of the body. It most commonly spreads to the nervous system, such as the spine or brain. It can also travel to the lungs. Symptoms of heart cancer that spreads include:
- Chronic back pain.
- Confusion or memory problems.
- Coughing up blood.
How is heart cancer diagnosed?
In people with heart cancer, healthcare providers often find the tumor while looking for the cause of heart problems. You may get one or more of these tests:
- Complete blood count (CBC).
- Chest X-rays.
- CT scan or MRI.
- Echocardiogram.
- Electrocardiogram (EKG).
- Coronary angiography and cardiac catheterization.
- Coronary computed tomography angiogram (CTA).
What are the complications of heart cancer?
Heart cancer affects your heart function. It can lead to a host of potentially life-threatening problems. With a heart tumor, you have a higher risk of having a heart attack, stroke or severe heart failure.
Small pieces of a heart tumor can break free and travel through the bloodstream. These pieces can lodge in a blood vessel, causing a blood clot that can lead to stroke if it goes to the brain, or respiratory problems if it goes to the lungs.
Heart cancer can affect the pericardium, the sac that surrounds the heart. Inflammation called pericarditis can result. Your healthcare provider may need to use a catheter (long, thin tube) to drain excess fluid and ease pressure on the heart and send the cells in the fluid for diagnostic analysis. This procedure is pericardiocentesis.
How is heart cancer managed or treated?
Chemotherapy or radiation therapy (or a combination of both) can sometimes shrink a heart tumor and relieve symptoms. If another cancer spread to the heart, your healthcare provider will treat that primary cancer.
Other treatment depends on the tumor location and size, as well as factors like your overall health and age. Surgery to remove the tumor may be an option, and has been shown to prolong life if it can be completely removed. These operations can be quite complex and are best performed at a specialty center. You may also be able to join a clinical trial to try promising new therapies still in development.
How can I prevent heart cancer?
Experts don’t fully understand why some people develop this rare cancer. Smoking contributes to many cancers and also leads to heart disease. Your healthcare provider can help you quit smoking.
What is the prognosis (outlook) for people who have heart cancer?
There isn’t a cure for heart cancer, and the disease is difficult to treat. After treatment, heart cancer often returns and may spread to other parts of the body.
The average life expectancy after a heart cancer diagnosis is about six months without surgical treatment, and greater than a year when surgery is possible with some reports of patients surviving several years after a complete resection of the tumor. It’s important to remember that researchers continue to look for better ways to detect this disease early, refine current treatments, and find new ones.
When should I call the doctor about heart cancer concerns?
You should call your healthcare provider if you experience:
- Changes in heart rate or rhythm.
- Chest pain or shortness of breath.
- Chronic back pain.
- Confusion or memory problems.
- Coughing up blood.
- Dizziness or fainting.
- What questions should I ask my doctor about heart cancer?
- You may want to ask your healthcare provider:
- What type of heart cancer do I have?
- What treatments can help?
- How can I manage treatment side effects?
- Should I look out for signs of complications?
A note from Cleveland Clinic
Because heart cancer is so rare, healthcare providers may misdiagnose the cause of heart problems. Specific diagnostic tests can help identify a heart tumor. If another cancer spreads to the heart, your provider will continue to treat that cancer. Standard cancer treatments like chemotherapy, radiation therapy and surgery can shrink or remove heart tumors and relieve symptoms. Researchers are exploring better ways to treat this uncommon disease.
You must be logged in to post a comment.