Why does IVF fail with Good Embryos

In vitro fertilization is a fertilization process where an egg is combined with a sperm in vitro. The process involves monitoring and stimulating a woman's ovulation process, removing an egg or ovum from the ovaries, and leaving the sperm to fertilize them in a culture medium in the laboratory.

Much information about in vitro fertilization (IVF) is now available to the public, which has made it more accessible, but there are still some lesser-known aspects of the treatment. People tend to think that IVF is a panacea for all infertility problems, and that there is almost a guarantee of success if one accepts this treatment method. However, this is not true. Even the best IVF center in Gurgaon cannot promise you success in IVF, despite being better than most other fertility centers in the country. On average, only about 30-40% of couples who receive this treatment are able to have a child. Why is that? This is because many factors play a role in a successful IVF cycle, and some of them are even beyond human control.

So if you are planning to have treatment or have had it fail, here are some possible causes of failure that you should know about.

Some common reasons for IVF failure

A common cause is a lower egg count; sometimes even ovulation drugs fail.

Poor egg quality is another possible cause

A lower sperm count also reduces the chances of fertilization

Poor sperm quality (low motility, deformed sperm or damaged sperm) can cause problems (you can check most of these problems with sperm test in Gurgaon)

Poor embryo quality or wrong selection of embryos can lead to premature abortion

Suboptimal laboratory conditions can lead to weakening or even death of embryos before implantation

Inaccurate and inefficient egg retrieval and/or embryo implantation are 2 critical errors in IVF that can cause cycle failure; implantation of an embryo outside the uterus can lead to an ectopic pregnancy that will soon end in miscarriage

A woman's age is a crucial factor, women under 35 have about a 50% chance of success, while women over 42 only have a 4% chance of conceiving.

Leading an unhealthy lifestyle can also lead to IVF failure

About 10% of IVF failures are attributed to unknown causes

To avoid most of these problems, you should choose an experienced doctor and the best IU I center in Gurgaon. However, there is another problem that some people face, their doctor has told them that the embryo is healthy, but they still have not been able to conceive. Let's see why this might happen.

Can IVF fail even with a good embryo?

Although a "good" embryo is necessary for continued pregnancy, it does not always guarantee IVF success. This is disappointing for digestion, but it can happen for 3 reasons. One, as mentioned above, poor implantation of even a healthy embryo will lead to IVF failure. Second, an apparently "good" embryo was thus declared by the embryologist based on morphological markers, which may be misleading, as the external form may not reveal qualitative problems. Sometimes an embryo has chromosomal abnormalities that cannot be detected based on its external appearance and require special screening tests to be diagnosed.

The third reason is a non-receptive uterus. Susceptibility can be caused by a condition such as endometriosis, fibroid, etc., or it can be the result of overactive immune cells causing the uterus to attack the embryo. Both of these conditions cause early miscarriage or even implantation failure (which, if it happens more than once, is called "recurrent implantation failure").

How to ensure IVF success after it has failed before?

Most couples experience difficulty in their first IVF cycle, some may even need 3 to 5 cycles to conceive. But no matter what the reasons were for earlier unsuccessful IVF cycles, you can still have hope for the future. You need to talk to your doctor about what happened. They may suggest various tests like laparoscopy, pre-implantation genetic screening (PGS), endometrial receptivity test (ERA), sperm DNA fragmentation test etc. to confirm the cause of failure. You will then need to work with your doctor to avoid these (or those) mistakes or treat underlying conditions before proceeding with the next IVF cycle. It is also better to take a break between two cycles, this will give the body and you the necessary time to recover from previous failed attempts and prepare for the next one. Finally, don't apply too much pressure, as anxiety can reduce your chances of conceiving. Just relax and try again if it helps, people have been known to get pregnant naturally after a few failed IVF cycles.

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