Skin cancer (SC) is the fifth most prevalent type of cancer and one of the most deadly diseases of the current decade [1, 2, 3]. It is also expected to overtake heart disease in the next decades as the leading cause of death and the largest barrier to raising life expectancy. In 2018, there were 18.1 million new cases of cancer worldwide and about 9.6 million cancer-related deaths, according to the International Agency for Research on Cancer's annual status report. According to data released by the American Cancer Society, among all malignancies, the number of new cases of melanoma is predicted to reach 4% for women and 6% for men in 2023. Additionally, it is anticipated that the quantity of new instances would keep rising.
Since skin cancer is the most frequent cancer globally and its incidence is increasing annually, it is a serious health concern. 1, 2, 3, and 4 Despite not being fatal, the majority of skin malignancies cause substantial morbidity and expensive therapy. Consequently, it is imperative to implement primary preventive techniques like sun protection or secondary prevention strategies like early identification by dermoscopy or reflectance confocal microscopy. 1, 5, 6, and 7
Furthermore, melanoma, squamous cell carcinoma, and Merkel cell carcinoma are among the skin malignancies that can be extremely aggressive and have a high fatality rate. 8 and 9 This has been particularly important during the COVID-19 epidemic, when skin cancer-related death rates have increased, possibly as a result of delayed identification.
papers describing uncommon tumors or uncommon correlations, like cutaneous metastatic endometrial carcinoma, a thorough analysis of malignant chondroid syringoma, a systematic review of the relationship between melanoma and genital lichen sclerosus, were duly included. Thirteen We think that in order to properly comprehend and treat these tumors, a deeper understanding of uncommon skin malignancies is crucial.
By comparing the melanoma outcomes of Black and White patients, we also hoped to further understanding of how skin cancer manifests in different ethnic groups. 16 While the majority of skin cancers are uncommon in non-white groups, the majority of studies conducted to date have concentrated on White populations, creating a knowledge bias that must be addressed.
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