What is Hyperhydrosis?
Hyperhidrosis is a condition of excessive sweating due to the overstimulation of cholinergic receptors on eccrine glands. In this condition, the body cooling system produces 4 to 5 times an average amount of Sweat.
Epidemiology Include 3% of the USA population
1% of the western population is affected by hyperhidrosis.
Onset- *childhood and adolescence in primary hyperhidrosis
* late age onset of secondary hyperhidrosis
Types- primary and secondary Hyperhydrosis
*Primary hyperhidrosis includes a chronic sweating concentration in one area of your body. It affects 2-3 percent population, has no known cause but has a family history
* Secondary hyperhidrosis is chronic sweating due to an underlying medical condition.
Pathology-* primary hyperhidrosis Genetics That is family history is positive.
*Secondary Hyperhydrosis due to medications like dopamine agonist, antipsychotic alcohol, and insulin disorders like Diabetes mellitus, hyperthyroidism, Parkinson's disease, tumors, chronic lymphoma infection.
Ares include -Palm, feet, axilla,
Pathophysiology- sweating beyond what the body uses for homeostatic temperature regulation. Eccrine glands concentrated areas such as the axilla, palm, sole, foot. Ach negative feedback is likely impaired in this patient, which may help explain how physiological response can become pathology hyperactivity of sympathetic nervous system excessive release of Ach will innervate epidermal sweat gland as your physiological response to core body temperature control during the time of physical or psychological stress.
Clinical features - clammy or wet Palm of hands
the clammy or wet sole
frequent sweating
sweating that source through clothing
irritating and painful skin problems like bacterial or fungal infections
Worrying about stained clothing
reluctant to make physical contact
self-conscious
socially withdrawn, sometimes leading to depression.
Medical conditions which cause hyperhidrosis are-
obesity
Stress
Menopause
anxiety disorder
diabetic hypoglycemia
hypothyroidism medication such as antidepressants
fever of unknown origin
heat exhaustion
HIV AIDS
Diagnosis-
history and physical examination -
age of onset in which age this condition occurs it can ultimately detect primary or secondary Hyperhydrosis.
Location - treatment can be according to that.
family history
The iodine starch test will define the area of Hyperhydrosis.
Laboratory and radiological examination- CBC
basic metabolic panel
thyroid-stimulating hormone
hba1c test
x-ray chest
segmentation
His Pathology - Eccrine glands have average size but have large sympathetic ganglia.
Treatment can be medications or surgery and Physiotherapy
Medications including the cholinergic drugs glycopyrrolate and beta-blockers which will help prevent stimulation of sweat glands Beta-blocker benzodiazepines help to reduce stress-related sweating
*antiperspirant aluminum chloride hexahydrate 3 or 4 Nights or as required
* Botox dose of purified b o t you l In I you m toxin is injected underarm temporally block nerves that stimulate sweating.
Some alterations in Lifestyle -including
clothing wear loose clothing some Fabricators nylon Can cause symptoms
* socks some socks are better at absorbing thick, soft sock.
*armpit pad in the armpit to protect from Sweat.
* shoe leather shoes are prescribed to the Hyperhydrosis patient.
Physiotherapy includes iontophoresis. It uses electricity temporarily to turn off this week as the most effective for Sweatt of hands and feet are immersed in the bowl of water small electric current of 15 to 20 milliampere current passes through water time 20 to 30 minutes required.
* laser use of microwave energy to create hi to destroyed sweat glands under arms affects our long-lasting treatment. Using local anesthesia to treatments three months apart helps reduce Sweat; it is only used for underarms.
Surgery may be required, such as a sweat gland resection in severe cases only.
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