DIARRHEA
DEFINITION:
Increase in stool BULK, FREQUENCY, or FLUIDITY, typically to volumes greater than 200 grams per day.
OR Loose, watery stools three or more times a day. Worldwide, diarrheal diseases account for greater than 700,000deaths of children under 5 years of age making them 2nd leading cause of death in this age group.
Diarrhea is not a disease but a symptom of other ailments. TYPES OF DIARRHEA Clinical types of diarrhea are: Acute watery diarrhea: o Lasts several hours or days. Acute bloody diarrhea o Also called dysentery. Chronic diarrhea o Persistent diarrhea lasts 14 days or extended Secretory diarrhea o STOOL consistency is isotonic (same) to blood.
It results from increased secretion from the gut (stomach small and large intestine), IT PERSISTS during fasting and after meals(IT MEAN NO FOOD ASSOCIATION) Malabsorption diarrhea-
It is caused by inadequate absorption of the nutrient. Associated with steatorrhea fatty stool, difficulty to flush. RELIVED by fasting. Exudate diarrhea-
It occurs due to inflammatory diseases
Characterized by purulent, bloody stool that continues during fasting. Osmotic diarrhea- It occurs due to LACTASE deficiency an enzyme. It breaks down lactose, a sugar in milk and milk products. Diarrheal fluid is 50mosmole more concentrated than plasma. Condition abates with fasting. GENERAL SIGNS AND SYMPTOMS OF DIARRHEA Signs and symptoms associated with diarrhea (loose, watery stools) may include Abdominal cramps or pain. Bloating. Seasickness.
Vomiting. High Temperature. Blood in the stool. Mucus in the stool. Urgent need to have a bowel movement. Painful spasm of the anal sphincter Epigastric pain Faintness
CAUSES:
there are so many causes of diarrhea but here important ones are enlisted below
1. Infections
Infections included
I. Bacterial infections
Some of them are enlisted as following Shigella –shigellosis Salmonella typhi-typhoid fever Campylobacter -campylobacter enterocolitis Mycobacterium tuberculosis Mycobacterium Bovis Mycobacterium avium
Vibrio cholera Escherichia coli Clostridium difficile ll. Viral infections Rotavirus Norovirus etc.
3. Parasitic infestation- Enterobius vermicularis Giardia lamblia Ancylostoma duodenale Necator americans Entamoeba histolytica etc.
2. Malabsorption of food
Poor absorption can occur in conditions like
Cystic fibrosis (the number one cause in the United States)
Chronic pancreatitis
Lactose intolerance
Celiac disease
Whipple disease
Shwachman-Diamond syndrome (a genetic disease affecting the pancreas and bone marrow)
Cow's milk protein intolerance
Soy milk protein intolerance
3. Intolerances to certain foods Celiac disease –wheat Lactose intolerance-milk, etc. 4. Medicines Sometimes medicine can cause diarrhea as their adverse effects. Some are registered below Antibiotics- Cephalosporins levofloxacin. ampicillin ETC. Antidepressants.- Some of them cause diarrhea They include: Citalopram Escitalopram Fluoxetine Paroxetine
Sertraline Antacids. Alka-Seltzer, Maalox Rolaids Rio pan, Proton pump inhibitors Omeprazole (Prilosec) Lansoprazole . 5. Chemotherapeutic agents 6. Radiation exposure
COMPLICATION OF DIARRHEA Dehydration-most fatal complication electrolyte imbalance micronutrients like vitamin and mineral deficiency failure to thrive acidosis Spared of infection ;
it includes UTI endocarditis osteomyelitis pneumonia meningitis septicemia peritonitis Hepatitis etc.
Reactive arthritis;
salmonella
Chlamydia Yersinia
Guillain Barre Syndrome; Campylobacter.
IGA nephropathy;
Campylobacter
Erythema nodosum; Campylobacter Yersinia
salmonella
Hemolytic uremic syndrome
E. coli
dysentery
Hemolytic anemia; Campylobacter Yersinia Kidney failure Organ damage etc. TAKE HOME MESSAGE Rehydration is vital Drink plenty of liquids, including water, broth, and juices. Avoid caffeine and alcohol during diarrhea Add semisolid and low-fiber foods gradually as your bowel movements return to normal.
ORS
Seek medical care
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