The research group led by Nicola Segata (Department of Cellular, Computational and Integrative Biology-Cibio of the University of Trento and European Institute of Oncology), which coordinated an international study on the acquisition of health-associated bacteria, tried to shed light on the issue. Eighteen institutions and research centers from all over the world were involved in the study, whose findings were published in Nature. The first author of the work is Mireia Valles-Colomer, a postdoctoral researcher at the Segata Lab of the UniTrento.
This is the largest and most diverse study to date on transmission of the human microbiome. The researchers investigated how bacteria are transmitted between generations (vertical transmission) and among people who live in close contact with each other, such as partners, children, or friends (horizontal transmission). They analyzed more than 9,000 stool and saliva samples from participants in 20 countries and all continents in the world.
The research group led by Nicola Segata (Department of Cellular, Computational and Integrative Biology-Cibio of the University of Trento and European Institute of Oncology), which coordinated an international study on the acquisition of health-associated bacteria, tried to shed light on the issue. Eighteen institutions and research centers from all over the world were involved in the study, whose findings were published in Nature. The first author of the work is Mireia Valles-Colomer, a postdoctoral researcher at the Segata Lab of the UniTrento.
This is the largest and most diverse study to date on transmission of the human microbiome. The researchers investigated how bacteria are transmitted between generations (vertical transmission) and among people who live in close contact with each other, such as partners, children, or friends (horizontal transmission). They analyzed more than 9,000 stool and saliva samples from participants in 20 countries and all continents in the world.
Mireia Valles-Colomer, who tracked the transmission of more than 800 species of bacteria, said, "We have found evidence of extensive sharing of the gut and oral microbiome linked to the type of relationship and lifestyle. The results suggest that social interactions actually shape the composition of our microbiomes. We have also found that certain bacteria, especially those that survive better outside our bodies, are transmitted much more often than others. Some of these are microbes from which we know very little, they have not even been named yet. This inspires us to study them better, as we still have many unanswered questions about the transmission mechanisms of the microbiome and how this affects our health."
Nicola Segata explained, "In adulthood, the sources of our microbiomes are mostly the people we are in close contact with. The duration of interactions—think for example of students or partners sharing an apartment—is roughly proportional to the number of bacteria exchanged."
In many cases, however, bacteria can spread even between individuals who have superficial and occasional interactions. "The transmission of the microbiome has important implications for our health," Segata continued, "since some non-communicable diseases (such as cardiovascular diseases, diabetes or cancer) are partly linked to an altered composition of the microbiome. The demonstration that the human microbiome is transmissible could suggest that some of these diseases (currently considered non-communicable) could, at least to a certain extent, be communicable. Further studies on the transmission of the microbiome can therefore advance the understanding of the risk factors of these diseases and, in the future, explore the possibility of reducing the risk with therapies that act on the microbiome or its transmissible components."
You must be logged in to post a comment.